Sore legs after drinking alcohol may be caused by physiological factors, generally more rest, drink more water can be relieved. It may also be caused by gout, allergies and other pathological factors, you should consult a doctor in a timely manner, according to the cause of the choice of physiotherapy or drug treatment. 1. Physiological factors: due to individual physical reasons, alcohol in the body after alcohol metabolism is not sufficient, may cause leg pain, drink more water, pay attention to rest, reduce activities, pain can generally be relieved, but also through hot compresses, massage to relieve pain. 2. Gout: drinking a lot of alcohol can lead to abnormal purine metabolism in the body, producing a large amount of uric acid, uric acid deposited in the joints of the legs, easy to induce gouty arthritis, which in turn leads to leg pain. You can take colchicine and other drugs under the guidance of a doctor. 3. Allergy:Some people will have alcohol allergy after drinking alcohol, leading to leg pain. Antihistamine drugs such as cetirizine hydrochloride can be taken orally under the guidance of a doctor, and first aid is needed when the situation is serious. Excessive calcium loss, rheumatic immune diseases can also cause symptoms of leg soreness after drinking, when the symptoms of leg soreness after drinking, you should consult a doctor in a timely manner to identify the cause, under the guidance of the doctor treatment.