Pathological manifestations of lymphoma: Malignant lymphoma is also one of the common malignant neoplastic diseases in clinical practice. Malignant lymphoma is pathologically divided into two major categories, Hodgkin’s disease and non-Hodgkin’s disease, which can be further divided into different types according to the size, morphology and distribution pattern of tumor cells. Hodgkin’s disease (hd) hd is a specific type of malignant lymphoma in which the histologic diagnosis relies primarily on finding characteristic r-s cells on a pleomorphic inflammatory infiltrative background. In 1965, the rye international conference identified four types: 1. Lymphocyte-dominant (lp)hd2 is dominated by medium and small lymphocytic proliferation, sometimes by histiocytic proliferation; typical r-s cells are not easily found. However, more l-h cells are often present. 2, nodular sclerosis type (ns) hd: characterized by double refractive broad collagen fiber bundles that separate lymphoid tissue with the presence of luminal type r-s cells into nodules of varying sizes; typical r-s cells are rare. 3, mixed cell type (mc) hd: typical r-s cells and h cells are numerous, inflammatory cells are obviously pleomorphic with vascular proliferation and fibrosis. 4, lymphocyte-ablative (ld) hd: in addition to the presence of typical r-s cells, many pleomorphic r-s cells (reticulocyte type) or diffuse non-bifollicular fibrous tissue hyperplasia with a significant reduction in reactive inflammatory cells may be present. Clinical manifestations 1. The main symptom or sign of malignant lymphoma is painless enlargement of superficial lymph nodes. Hodgkin’s disease usually has cervical or supraclavicular lymph node involvement. nhl In addition to the involvement of supra- and inferior diaphragmatic lymph nodes, other lymph-like tissue sites such as talipes, foveal lymph nodes and Wechsler’s ring invasion can be found upon careful clinical examination. 2.Symptoms such as fever, night sweats or weight loss may be present. 3.Itchy skin is more common in Hodgkin’s disease than nhl and is usually treated ineffectively with antihistamines. 4.Patients with Hodgkin’s disease occasionally experience pain after drinking alcohol, and the pain is confined to the affected area. 5. In addition to enlarged lymph nodes, splenomegaly can be found on physical examination. Patients with splenomegaly often have hepatomegaly. In advanced stage, patients with enlarged mediastinal lymph nodes may have superior vena cava obstruction. Pathological manifestations of lymphoma: Through the above introduction, I hope you understand the pathological manifestations and clinical symptoms of lymphoma, the main reason for the occurrence of lymphoma is related to people’s living habits, physical quality and diet, so it is very helpful to develop good living habits to prevent the occurrence of lymphoma.