The five-year survival rate of patients with stage III moderately differentiated colon cancer is about 70% after treatment, and the prognosis is relatively good. Moderately differentiated colon cancer is a malignant tumor caused by poor dietary habits, heredity and other factors. Moderately differentiated represents general malignancy and general prognosis of the tumor; stage Ⅲ represents the disease condition that the tumor invades the submucosal layer or the intrinsic muscular layer, 1-3 regional lymph node metastases occur, and there is no distant metastasis, etc. If there is a chance of surgery in this period, surgical resection is often performed. In this period, if there is a chance of surgery, surgical resection is often performed, and after surgery, chemotherapy is supplemented according to the condition, and the commonly used chemotherapy regimen is oxaliplatin combined with capecitabine, which needs to be applied under the guidance of doctors. After active treatment, about 70% of five-year survival rate can be obtained, and attention to regular review after surgery can prolong the survival period to a certain extent.