High total bilirubin in liver function tests indicates that liver function has been damaged, and the causes are mainly the following: 1, viral hepatitis, especially viral hepatitis B, which is the most common cause of liver function damage in our population, at this time, in addition to high total bilirubin, patients may also have elevated ghrelin and glutamic oxalacetic aminotransferase. 2, various causes of cirrhosis, hepatitis B, long-term alcohol abuse, etc. 3, liver damage caused by physical and chemical factors, various physical and chemical factors, such as drugs, trauma, etc., may lead to liver function damage, resulting in elevated bilirubin. 4, hemolytic anemia, such as serum sickness, hemolytic anemia, etc., can also lead to elevated total bilirubin, which is mainly due to the destruction of blood red blood cells for various reasons, bilirubin is released into the blood in large quantities. This is mainly due to the destruction of red blood cells and the release of large amounts of bilirubin into the blood, which is not caused by liver function damage. In short, there are many reasons for high total bilirubin, so it is best to go to the hospital immediately for examination to clarify the cause.