The difference between Chlorosartan Potassium Tablets and Irbesartan Tablets is mainly manifested in pharmacological effects and clinical applications. 1. Pharmacological effects: both belong to angiotensin receptor blocking drugs, but Irbesartan has 10 times higher affinity for AT1 receptor than Chlorosartan Potassium Tablets; while Chlorosartan Potassium Tablets have higher affinity for AT2 receptor than Irbesartan. 2. Clinical application: Irbesartan is suitable for the treatment of essential hypertension, combined with hypertension in the treatment of type 2 diabetic nephropathy; Chlorosartan Potassium Tablets are only used for the treatment of essential hypertension, and have no therapeutic effect on type 2 diabetic nephropathy. 3. Adverse reactions: Irbesartan see adverse reactions for mild headache, dizziness, palpitations, etc., occasionally cough, the adverse reactions of potassium chlorosartan tablets are less, occasionally see facial swelling, fever, postural hypotension. 4. Contraindications: Both are only used for patients who are allergic to angiotensin receptor inhibitors, and pregnant and lactating women. It is recommended to use the drug under the guidance of a doctor and follow the doctor’s instructions to standardize the treatment.