Lumbar disc herniation with closed injection can relieve pain, but there are some side effects, such as vascular nerve damage, centripetal obesity. Lumbar disc herniation can compress the nerve root, and symptoms such as lumbago and sciatica appear, if the patient has long-term pain, the symptoms can be relieved by taking closed injections. Closed injection, that is, through the lidocaine and other anesthetic drugs mixed with methylprednisolone and then injected into the lesion area, so as to achieve the purpose of relieving pain and reducing inflammation. During the injection, blood vessels and nerves may be damaged. Because the drug contains hormones, if large doses are applied repeatedly for a long period of time, patients may develop centripetal obesity, prolonged wound healing, and may induce aseptic necrosis of the femoral head and osteoporosis. If there is a history of gastric ulcer disease will also aggravate gastrointestinal ulcer disease. Allergy to hormone drugs is prohibited. If the diagnosis of lumbar disc herniation is confirmed, it is recommended to carry out standardized treatment under the guidance of a doctor as soon as possible in order to reduce the adverse effects of the disease.