Men may also be infected with HPV (human papillomavirus) virus, mainly related to unclean sexual life and unclean hygiene habits. Common clinical HPV infections include condyloma acuminatum and penile cancer, both of which are related to HPV infection. When one of the partners has HPV infection, after unsafe sex, it is possible for the other partner to be infected with HPV virus, i.e. the chances of men and women being co-infected with HPV virus are higher. The HPV infection in men may not show specific symptoms, but is only found through screening. 10% of men with glansitis may be infected with HPV, and the rate of HPV infection is also higher in homosexual or bisexual men, especially those with irregular sexual partners and those who do not pay attention to glans hygiene, need to pay attention and recommend regular checkups. High-risk or specific types of HPV infection may cause other lesions, such as condyloma acuminata, and even induce penile cancer. The most important thing is that you should be aware of the fact that there are no obvious clinical manifestations in the early stages of the infection. Later on, there will be skin flora in the coronal groove, glans, foreskin, urethra and anal area, which are usually clustered or cauliflower-like, hard in texture, and may be brown, brown or black. In summary, men must pay attention to the hygiene of their sexual life, wash frequently, change underwear in time and keep the area dry. If one partner is tested for HPV infection, it is recommended that the spouse be examined and treated together.