Medobar is the main drug for the treatment of Parkinson’s disease, generally diagnosed with Parkinson’s disease, patients are often the first to take Medobar, and need to take long-term, this is due to the reduction of nigrostriatal cells in the brain of Parkinson’s patients, can not produce the dopamine transmitter required to maintain the normal body, the motor balance is broken, there are Parkinson’s disease symptoms. Medobar drug is a dopamine replacement, taking Medobar is to give compensation from the outside to meet the normal needs of the body, so as to effectively improve the symptoms of Parkinson’s disease, but can often hear many patients complaining that taking Medobar is not effective, this is why? 1, the patient is not Parkinson’s disease, but Parkinson’s syndrome Some patients will not clearly improve even if they take larger doses of Medobar. This is to consider that the patient may be Parkinson’s superimposed syndrome or secondary Parkinson’s syndrome (drugs, trauma, stroke and other secondary Parkinson’s), rather than primary Parkinson’s disease. Further systematic examination and analysis is needed to determine the specific type and to carry out targeted treatment. 2, the drug effect does not reach the patient’s desired state Some patients wrongly believe that after taking Medobar, the condition should be completely improved, like normal people, if the drug effect does not reach their ideal state, they think Medobar is not effective, and exaggerate the truth to tell the doctor. If the doctor judges the patient to be Parkinson’s syndrome based only on the subjective information provided by the patient, he or she may abandon effective Parkinson’s drug therapy. Some patients are convinced that “the side effects of drugs are very big” and have a fear of Medobar and other drugs, and do not take enough doses of Medobar, so that the concentration of drugs in the body is not enough to reach the que value needed to take effect, so it does not produce an effective effect. 4, different symptoms, Medobar efficacy is different Some patients are mainly typical muscle tonicity and bradykinesia, taking Medobar is more effective, while some patients with tremor-based or “freezing gait”, such Parkinson’s symptoms on Medobar’s efficacy response is not as good as the former. However, this does not determine that the patient’s poor efficacy belongs to Parkinson’s syndrome. 5, the past effective, the current efficacy of poor Some patients taking Medobar used to be effective, but now the efficacy is reduced, the efficacy of the maintenance time is shortened, but there is still a significant difference in the state before and after taking the drug, which belongs to the end of the dose phenomenon or motor fluctuations. Need to systematically adjust the drug or combined with brain pacemaker surgery treatment, generally will achieve good results. 6, the time to take the drug is not separated from the time to eat Many people may immediately after eating Medopa drugs, and vice versa, but according to research has found that some amino acid components in food protein will affect Medopa drugs into the brain to take effect, there is too much fat in the diet will also delay the absorption of Medopa drugs, so after eating can not immediately take Medopa drugs, but should be time forked, generally recommended one hour before meals or Two hours after the meal to take the drug, so as to ensure that the drug is fully absorbed, but also to ensure that the body’s nutritional needs. In summary, I hope that patients and their families can correctly analyze the causes, scientific and effective treatment.