Hyperthyroidism is the short form of hyperthyroidism, and hyperthyroid patients are clinically advised to quit smoking, so hyperthyroid patients should not smoke. Cigarettes contain a large amount of nicotine, which causes abnormal excitation of the body’s sympathetic nerves, which may lead to the aggravation of the symptoms of hyperthyroidism. In addition, when hyperthyroidism patients develop thyroid-related eye disease, smoking may lead to worsening symptoms of proptosis, and smoking is one of the risk factors for the development or aggravation of infiltrative proptosis. Therefore, patients with hyperthyroidism should follow their doctor’s advice to quit smoking during treatment. It is recommended that patients with hyperthyroidism follow the doctor’s instructions for standardized treatment, and should quit smoking in their daily lives to avoid aggravating their condition and triggering adverse consequences.