The following causes of facial swelling are considered: 1) abnormal kidney function; 2) nephrotoxicity of the drugs applied; 3) more fluid in the drip, resulting in temporary water and sodium retention, causing facial swelling. For people with underlying kidney disease, after taking in too much water in a short period of time will lead to water-sodium retention, and the kidneys cannot excrete the excess water out of the body quickly, which will lead to puffiness. Therefore, this possibility should be ruled out first, and a kidney function test is recommended. In addition, some drugs are nephrotoxic, and their application can lead to kidney function damage and decrease in kidney drainage capacity, which can also cause swelling, and this situation also requires kidney function check, which needs to be combined with specific drugs. The last case is physiological factors, which is due to excessive dripping in a short period of time, the kidneys can not drain the excess water out of the body for a while, it will cause transient edema, this situation does not require special treatment, but also need to exclude pathological factors before considering this possibility.