Red degeneration of 10CM fibroid may be due to benign lesions caused by blood circulation disorders, which usually appear during pregnancy and puerperium, and may be related to pregnancy and high blood pressure during pregnancy. 1. Pregnancy: Placental prolactin produced during pregnancy will stimulate estrogen, leading to a sharp increase in the size of uterine fibroids, which will lead to blood circulation disorders within the tumor, resulting in congestion, edema, thrombosis, etc., which will lead to ischemic changes, and the infiltration of hemoglobin into the fibroid tissues, which may lead to the red degeneration of the 10CM fibroids. 2. Hypertension during pregnancy: due to high blood pressure during pregnancy and other reasons, it will not only lead to vascular lesions, but also affect the vascular lesions around the leiomyosarcoma, leading to the blood transportation obstacle of the leiomyosarcoma, and the appearance of 10CM leiomyosarcoma red degeneration. Therefore, patients with 10CM leiomyosarcoma red degeneration should go to the hospital as soon as possible to clarify the cause of the disease and carry out standardized treatment under the guidance of doctors.