There are many ways to treat the swelling of lower limbs caused by renal failure, such as diuresis, allopathic treatment and dialysis. 1. Diuretic: Diuretic treatment can be carried out through the use of many kinds of diuretics, such as furosemide, torasemide and other drugs, so as to alleviate the problem of lower limb swelling caused by renal failure. 2. Causal treatment: It is necessary to know the cause of edema, such as caused by excessive protein loss, can use human albumin and other drugs to supplement protein. If it is caused by hypertensive nephropathy or diabetic nephropathy, it is necessary to actively control the blood pressure and blood glucose level, as well as to control the salt intake, etc. Commonly used antihypertensive drugs include captopril and valsartan, and glucose-lowering drugs include acarbose and insulin. 3. Dialysis: Patients who meet the indications for dialysis can also choose dialysis, peritoneal dialysis or hemodialysis according to the specific conditions of the patients, so as to relieve the symptoms of swelling of the lower limbs. There are many ways to relieve the swelling of lower limbs caused by renal failure, it is recommended to go to regular hospitals, to clarify the cause and severity of the disease, and actively cooperate with doctors to avoid blind treatment.