Bitter breath and bad breath in the morning when you wake up may be due to physiological reasons or gingivitis and other oral diseases, gastroesophageal reflux and other digestive disorders and other reasons, need to be targeted to deal with. 1. Physiological reasons: due to the presence of some food debris or soft dirt in the mouth itself, these things in the mouth to stay overnight may be corrupted to appear bitter halitosis. In addition, frequent smoking, drinking alcohol and eating too spicy and stimulating can also appear in the morning wake up bitter bad breath. Can be improved by adequate oral cleaning, quit smoking and drinking, eat a light diet. 2. Gingivitis: a large number of bacteria adhere to plaque and calculus, and then cause gingivitis, which can be manifested as bitter mouth and bad breath. You can choose to use compound chlorhexidine gargle for gargling, can also be applied externally iodine glycerin anti-inflammatory, and also pay attention to oral hygiene, the inflammation subsides in time to remove dental calculus. 3. Gastroesophageal reflux: due to the relaxation of the lower esophageal sphincter and other reasons leading to gastric reflux, can appear in the morning after waking up bitter mouth, bad breath, and epigastric burning sensation, belching and other manifestations. Treatment can choose omeprazole enteric-coated capsules, magnesium aluminum carbonate chewable tablets and other drugs to inhibit the secretion of gastric acid, protect the gastric mucosa and other treatments, through the treatment of the cause of the disease to improve the manifestation of bitter mouth, bad breath. In addition, the existence of cholecystitis, gastric ulcer and other diseases can not be ruled out, it is recommended to consult a professional doctor for diagnosis and treatment. All of the above drugs should be used under the guidance of a professional doctor.