I. How to interpret the clinical significance of glucose tolerance test? 1.When intravenous fasting blood glucose <6.1mmol/L and two-hour blood glucose <7.8mmol/L after taking glucose, it means that the human body has normal ability to regulate blood glucose after taking glucose, which is normal for glucose tolerance. 2.When intravenous fasting blood sugar ≥7.0mmol/L or OGTT two-hour blood sugar ≥11.1mmol/L, it means that the human body's ability to deal with glucose after taking it is significantly reduced, and the diagnostic standard of diabetes has been reached. 3.When the intravenous fasting blood glucose <7.0mmol/L and the OGTT two-hour blood glucose is between 7.8 and 11.1mmol/L, it means that the human body's ability to regulate glucose is mildly reduced, and the diagnostic standard of low glucose tolerance has been reached. 4. When the venous fasting blood glucose is between 6.1~7.0mmol/L and the OGTT two-hour blood glucose is ≤7.8mmol/L, it means that the human body has good ability to regulate blood glucose after taking glucose, but the ability to regulate fasting blood glucose is mildly reduced, and it has reached the diagnostic standard of impaired fasting blood glucose. II. What are the factors affecting the results of glucose tolerance? 1. Diet before the test Excessive restriction of carbohydrate diet before the test can reduce the glucose tolerance, and the test result will be false positive. Therefore, before measuring glucose tolerance, it is necessary to ensure a normal diet, which should not be less than 150g of carbohydrates per day for at least 3 days, so that the test results will be accurate. For those who are severely malnourished, they need to improve their nutrition for a period of time before testing. 2.Physical activity Long-term bedridden patients can have impaired glucose tolerance. Strenuous activity before the test can accelerate the utilization of glucose, but due to sympathetic excitement, catecholamines and other glucose-raising hormones are released, which can increase blood glucose, so the patient should sit or rest quietly for at least 0.5 hours before the test. 3, mental factors Emotional excitement can make sympathetic excitement and blood sugar rise, so mental stimulation should be avoided during the test. Diseases and traumas such as acute myocardial infarction, cerebrovascular disease, surgery and burns are all stressful conditions that can temporarily increase blood glucose and reduce glucose tolerance, and endocrine diseases such as hyperthyroidism or vomiting and diarrhea can also affect blood glucose. Therefore, it is not suitable to do glucose tolerance test when you are sick, and you should wait until you recover from illness and resume normal activities before doing this test. 5. Drug factors Glucocorticoids, certain antihypertensive drugs and other drugs can affect blood sugar, making it rise, fall or fluctuate. However, drugs should not be stopped without authorization in order to exclude the influence of drugs on blood glucose, and a professional endocrinologist should be consulted to decide whether a glucose tolerance test can be performed. The last two points need to be noted: 1. In practical application, the glucose tolerance test can also be simplified, i.e., only 2 hours after taking fasting and 75g of glucose specimens to determine the blood glucose value, and the 2-hour value is generally considered to be critical. For patients with hypertension, dyslipidemia, obesity, a history of coronary heart disease, a history of gestational diabetes and people over 40 years of age should be more vigilant and should take the initiative to do diabetes screening. 2, because those with obvious diabetic symptoms and higher than normal fasting blood glucose are usually diagnosed with diabetes, it is not recommended clinically to do glucose tolerance test again, if this test must be performed, 100 grams of white bread can be used instead of 75 grams of glucose, we become the "bread meal test", the same extraction of venous blood to test blood glucose The diagnostic significance is also the same.