The diagnostic criteria for late-onset autoimmune diabetes mellitus in adults include the following four points: 1. Adult onset: The criterion for adults in China is greater than 14 years of age. 2. Delayed onset or slow progression: spontaneous ketosis or ketoacidosis is more than six months from the first appearance of diabetic symptoms or diagnosis. Previous domestic and foreign reports are generally three years, and in recent years, domestic reports are mostly three to five years. 3, autoimmune-mediated: The presence of autoimmune-mediated mechanisms can be clinically determined by testing autoimmune markers, but it should be noted that the inadequacy of the measurement method may lead to false negatives. 4, type 1 diabetes: LADA belongs to a subtype of type 1 diabetes, so the final localization remains as type 1 diabetes.