In the middle of the night, anal pain and want to go to the toilet, may be caused by sinusitis, hemorrhoids, perianal abscess and other reasons. 1. Sinusitis: sinusitis is generally caused by bacterial infection, mostly associated with fecal stimulation, consumption of a large number of spicy and irritating food and other factors, the onset of the patient will appear defecation, anal distension of the symptoms, the patient’s anal canal will appear to fall, and accompanied by pain, itching symptoms. 2. Hemorrhoids: hemorrhoids are mostly associated with poor defecation habits, eating habits, obesity and other factors, patients generally have no symptoms in the early stage, with the development of the disease, patients will appear anal discomfort, such as itching, pain, some patients will also appear mild incontinence, perianal distension and other symptoms. 3. Perianal abscess: perianal abscess is mostly related to trauma, infection, low immunity and other factors, the onset of the patient’s perianal persistent pain, pain will be aggravated by the pressure, the patient will also appear in the anxious and heavy, anorectal distension, some patients will also be accompanied by chills, fever, fatigue and other symptoms. Appear in the middle of the night anal swelling pain want to go to the toilet, may also be other reasons, such as rectal tumors, etc., should be timely to the hospital for consultation, diagnosis and treatment as prescribed by the doctor, to avoid delays in the condition.