The difference between gout and rheumatoid arthritis lies in the etiology, symptoms and laboratory tests. 1. Causes: Gout is a joint inflammation caused by the deposition of urate crystals in the joints and surrounding soft tissues due to abnormal uric acid metabolism, etc. The specific cause of rheumatoid arthritis is not yet clear, and it is currently considered to be an autoimmune disease. 2. Symptoms: The common symptoms of gout patients are severe joint pain and joint swelling, some patients may have fever and headache, etc. The common symptoms of rheumatoid arthritis patients are morning stiffness, joint pain and joint swelling, and in the late stage, there may be difficulty in joint movement and joint deformity. 3. Laboratory tests: rheumatoid arthritis and autoimmune system disorders are closely related, so rheumatoid arthritis patients laboratory tests can appear positive autoantibodies such as anti-CCP, rheumatoid factor, etc., and gout and uric acid metabolism disorders, so patients with gout uric acid test will generally appear uric acid elevation. Patients with gout and rheumatoid arthritis are advised to go to the rheumatology and immunology departments of regular hospitals for detailed consultation and treatment as prescribed by doctors.