Runny nose and fever are considered as upper respiratory tract infection, the common causative agent is virus, besides virus it may also be bacteria or atypical pathogenic bacteria. Virus is characterized by normal or below normal white blood cells, elevated or decreased lymphocytes, increased monocytes appear, C-reactive protein and calcitoninogen will not increase. After the diagnosis of viral infection, symptomatic, antipyretic and detoxification treatment can be taken, such as when the patient has high fever and body temperature >38.5℃, febrifuge, loxoprofen sodium, ibuprofen extended-release solution and other related drugs can be taken orally for antipyretic treatment, commonly used antipyretic and detoxification Drugs include Qing Kai Ling or Pu Di Lan. If the patient has yellow sputum, bacterial infection is considered and the white blood cells will increase. Oral antibiotics can be taken for treatment, commonly used antibiotics include amoxicillin, penicillin v potassium tablets, cefaclor, azithromycin, etc.