The causes of a sore throat that keeps drooling out of the mouth may include acute pharyngitis, acute tonsillitis, and acute epiglottitis. It can be treated by general care and medication. 1. Acute pharyngitis: manifested as dry, itchy throat, obvious pain, inflammation stimulation of the pharyngeal mucosa caused by the symptom of wanting to spit. The patient should rest more, drink water, at the same time can follow the doctor’s instructions to take dulcimer containing tablets, iodine throat tablets, etc. to relieve the symptoms, can also be used to furacilin gargle, compound chlorhexidine gargle, etc. gargle, local anti-inflammatory and clean throat. 2. Acute tonsillitis: manifested as severe sore throat, sore throat aggravated by swallowing, at the same time can cause increased tonsillar secretion, causing the feeling of wanting to spit. Patients should pay attention to rest, drink more water, eat light, nutritious food, and at the same time can follow the doctor’s instructions to take drugs such as amoxicillin, cefaclor, etc. for treatment. 3. Acute epiglottitis: direct stimulation of the epiglottis when doing swallowing or eating, resulting in increased throat pain, causing drooling and reluctance to eat. Patients can follow the doctor’s instructions to use drugs such as amoxicillin clavulanate potassium, cefixime and dexamethasone for treatment. If the sore throat has been out of the saliva of the symptoms continue not to ease, we should consult a doctor to clarify the diagnosis, follow the doctor’s instructions to standardize the use of medication and treatment, do not blindly use their own medication, so as to avoid delays in the condition.