The causes of knee pain when climbing stairs include osteoarthritis, synovitis or acute injury, which can be treated with medication or surgery. 1. Osteoarthritis: clinically, you can take oral celecoxib capsules, etoricoxib tablets, aminoglycosyl chondroitin calcium tablets and other medications under the guidance of a professional doctor, if the drug treatment does not achieve good results, you can take artificial joint replacement, joint fusion or articular cartilage repair and other surgical procedures for treatment. 2. Synovitis: clinically, it can be treated by oral ibuprofen tablets, diclofenac sodium extended-release tablets and other drugs, and if necessary, it can be treated by radiofrequency ablation or synovectomy, etc. The two-pronged approach can play a very good therapeutic effect. 3. Acute injury: clinically, it can be treated by oral diclofenac sodium extended-release tablets, celecoxib capsules or ibuprofen tablets and other painkillers. As each patient’s physical condition is different, the corresponding treatment plan is also different, it is recommended to go to the hospital in time, after clarifying the cause of the disease, under the guidance of a professional doctor to carry out standardized treatment. The use of medication should be in accordance with medical advice.