Glycine insulin and acarbose does not exist which is effective, glycine insulin and acarbose indications, adverse reactions, contraindications are different, specific under the guidance of the doctor combined with the actual situation of the patient to choose the patient’s most suitable drugs. Glycine insulin is an insulin analog with a long-acting effect, used for diabetes requiring insulin treatment, such as type 1 diabetes, diabetes complications, in pregnancy and childbirth and other states. A common adverse reaction is hypoglycemia. It is contraindicated in people who are allergic to glucagon, and in diabetic ketoacidosis. Acarbose is a glycosidase inhibitor and is used in the treatment of type 2 diabetes mellitus to lower postprandial blood glucose in people with impaired glucose tolerance. Common adverse reactions are flatulence, diarrhea, gastrointestinal and abdominal pain. It is contraindicated in diabetic ketoacidosis, hypersensitivity to acarbose, inflammatory bowel disease, severe hepatic or renal insufficiency, pregnancy, and lactation. Patients are also advised to eat a diabetic diet, eat regularly, regularly, regular exercise and standardized treatment under the guidance of a doctor.