Determination of syphilis in women can be based on clinical manifestations, laboratory tests and other aspects. 1. Clinical manifestations: women with stage I syphilis may develop painless ulcers on the external genitalia, and when it develops into stage II syphilis, the rash may involve the trunk and limbs, and syphilitic baldness may occur. If a woman has progressed to stage III syphilis, the main manifestation is irreversible damage to the skin, mucous membranes and other organs. 2. Laboratory tests: laboratory tests are mainly syphilis serologic examination, women infected with syphilis spirochetes about 4 to 10 weeks, the serum will produce a certain amount of antibodies, which is an important method of diagnosis of syphilis. The clinical manifestations of each syphilis patient may be slightly different, if suspected of being infected with syphilis, it is recommended to consult a doctor in time and follow the doctor’s instructions to carry out the relevant tests to clarify the diagnosis so as not to delay the condition.