Understanding the early manifestations of a relapse of schizophrenia can be of great help to family members in observing the condition, seeking timely medical attention, and reducing the aggravation of the condition. To summarize, there are the following: 1, sleep and life pattern changes: such as the sudden appearance of insomnia, sleepless nights, get up and walk around, go out, or life pattern out of control, stay out all night, etc., may be an early manifestation of relapse of the disease. 2. Denial of having the disease: Most patients can recognize that they have the disease after treatment. If the patient does not think she is sick, or pesters her family “why do you take medication”, “why did you send her to hospital?” If the patient does not think she is sick, or does not think the previous symptoms are sick, it may be a sign of relapse. 3. Unauthorized medication reduction or discontinuation: If a patient suddenly appears unwilling to take medication, or reduces medication on her own, thinking that she is well and does not need to take medication anymore, or hides medication on her own, it is also a sign of relapse. 4, mood, behavior, thinking changes: such as the emergence of anxiety, depression, irritable. Throwing tantrums for no reason, often leaving without saying goodbye, dazed, alone, and unhygienic. Asking some inexplicable and absurd questions or having some bizarre and weird ideas are also manifestations of relapse. Of course, the above-mentioned symptoms are not all the symptoms of relapse, nor are they specific, but if the patient shows any of them, he should contact the doctor or go to the hospital for examination in time, so as to reduce the aggravation of the disease and re-hospitalization, and also to avoid the occurrence of injuries and self-injury.