Leukoplakia is vitiligo and can present as white patches on any part of the body. Typical lesions are milky white pigment loss spots. Progressive white patches may expand and increase, forming tricolor vitiligo, with no self-conscious symptoms. Including drug treatment, phototherapy, depigmentation, transplantation treatment and other ways. 1. medication: topical drugs using glucocorticoids such as dexamethasone, applied to the white spots, the range should be less than 10% of the body surface area, the effect of the progressive stage is better. At the same time, you can use calcium-modulated phosphatase inhibitors, you can use pimecrolimus ointment, tacrolimus ointment for coating. Vitamin D3 derivatives can also be used, including calcipotriol and tacrolimus ointment. 2. Phototherapy and depigmentation: Phototherapy is applicable to all types of vitiligo treatment. Depigmentation applies to white spot area greater than 95% of the body surface area, resistance to various repigmentation treatments. After depigmentation, pay attention to sun protection. 3. transplantation therapy: applicable to stable segmental, and unclassified. Autologous epidermis and melanocytes are transplanted to the depigmented area to achieve the purpose of color restoration. Leukoplakia treatment should not self-medication, need to seek medical treatment as soon as possible to avoid causing adverse complications.