There is no absolute fastest and most effective way to get a headache after drinking, you can take drugs, massage and other ways to relieve, while paying attention to adjusting lifestyle, the specific effect varies from person to person. Headache after drinking can take painkillers for relief, commonly used drugs for aspirin, ibuprofen, acetaminophen and other non-steroidal anti-inflammatory drugs. You can also take massage, hot compresses and other methods, which are conducive to pain relief. In addition, you need to drink more water, eat more light food, avoid drinking alcohol, coffee, strong tea and so on. Rest more, avoid staying up late and do not overwork. If the headache after drinking is not relieved for a long time, it is recommended to consult a doctor in time for targeted treatment.