Mothers who are generally over 35 years of age are considered to be of advanced maternal age. Mothers of advanced maternal age have a higher risk of pregnancy compared to younger mothers. Older pregnant women have a higher risk of spontaneous abortion and embryonic arrest in the early stages of pregnancy, which is mainly related to the quality of the eggs and embryos. Because the probability of chromosomal abnormalities in eggs increases greatly with age, women of advanced age are not only less likely to become pregnant, but also susceptible to embryonic arrest due to chromosomal abnormalities in the fetus after pregnancy. What is Embryonic Fertilization? Embryonic arrest is a phenomenon in which the embryo develops abnormally in the early stages of pregnancy. A fertilized egg is like a seed that undergoes a series of complex and wonderful processes to grow into a healthy baby. If the fertilized egg fails to germinate at the initial stage, it is likely to stop growing and the embryo will become sterile. In the vast majority of cases, embryonic sterilizations are a process of survival of the fittest, with over 70% of embryos dying and being expelled because the embryo itself is not doing well, and after a certain level of development, the embryo is unable to grow any further. As a matter of fact, the majority of early miscarriages have no specific cause, and only a small percentage of them can be found. What tests are done for embryo termination? In the case of one embryonic arrest, there is no need for any special tests and the pregnancy can continue to be attempted after 3 months. If there are more than 2 embryo stops, it is recommended to go to a fertility center to do relevant tests, and both male partners need to be tested. For the woman, the main investigations are as follows: endocrine factors, coagulation factors, immune factors, uterine factors, chromosomal factors, infectious factors and so on. Endocrine factors, especially basic endocrine, are very important and are one of the necessary tests. Coagulation tests are also necessary for women with a history of embryonic abruption. Immune-related tests include antinuclear antibodies, anti-double-stranded DNA antibodies, anticardiolipin antibodies, anti-beta2 glycoprotein antibodies, D-dimer, homocysteine, etc. If these tests are abnormal, treatment is required. Uterine factor is to check whether there is any malformation or abnormality in the uterus. Since the risk of embryo termination is higher in older women than in younger pregnant women, chromosome is an indispensable test when there are more than 2 embryo terminations. In the male partner, the main tests are sperm and chromosomes. For example, abnormal sperm DNA fragmentation (DFI) can affect the developmental potential of the embryo. Chromosomal abnormalities in the male partner can also cause embryonic failure. Therefore, if you have had more than two embryonic failures, you can bring your male partner to our fertility center, and the doctor will examine your specific situation and treat you accordingly.