Thigh lymphatic pain clinically mostly refers to pain in the inguinal lymph nodes, and is mainly considered to be related to pathological factors such as lower limb lymphadenitis, acute lymphadenitis, lymphoma, malignant tumors and so on. 1. Lower limb lymphadenitis: also known as dengue (acute infectious disease, visible redness of the skin like paint), mostly secondary to trauma, tinea pedis and other soft tissue infections, which can be manifested as inguinal lymph node swelling, pain, fever and other symptoms. 2. Acute lymphadenitis: when the autoimmune function decreases, the body will be susceptible to bacterial, viral and other infections, which invade the lymph nodes in the groin area through the lymphatic vessels, thus causing acute inflammation leading to pain in the lymphatic region of the thigh. 3. Lymphoma: it belongs to the disease of blood system, in addition to the swelling and pain of inguinal lymph nodes, it can also be accompanied by fever, itching and other symptoms. 4. Malignant tumor: cancer cells of malignant tumor patients may be metastasized through lymphatic channels, and when invaded to thigh, it may cause symptoms of swelling and pain in inguinal lymph nodes. For those who have swollen and painful inguinal lymph nodes, it is recommended to go to the hospital in time to improve the blood routine and other systematic examinations, and then treat the cause of the disease positively after clarifying the cause, so as to avoid delaying the condition.