Platelets rise and then fall after taking prednisone, it may be that the efficacy of the treatment is not achieved, or there is no symptomatic treatment.
1. No symptomatic treatment: Prednisone is used to treat connective tissue disease, severe bronchial asthma, systemic lupus erythematosus, vasculitis, dermatomyositis, acute leukemia and other diseases. After taking prednisone, its inhibition of the body’s immune system, platelet elevation; if the disease does not belong to the indications of prednisone, there may be a rise and then fall.
2. The therapeutic effect is not achieved: if the disease is within the therapeutic range of the drug, but the dosage is insufficient, the therapeutic effect is not achieved, when the concentration of the drug in the body decreases, it is not enough to continue to inhibit the immune system, and the immune system becomes active again, the platelets will be inhibited, so there is a situation that rises first and then falls.
3. The nature of the disease itself is determined. Certain diseases such as acute lymphoblastic leukemia chemotherapy program contains prednisone, if the leukemia remission after chemotherapy platelets will rise, but acute leukemia chemotherapy remission has a certain relapse rate, once the relapse, platelets will also fall.
In patients with primary immune thrombocytopenia, prednisone or dexamethasone is preferred for initial treatment. The effective rate is very high, however, this disease is characterized by easy recurrence, once recurrence, platelets will also fall.
It is recommended to consult a doctor in time to identify the cause of the disease and treat the symptoms.