Intolerable knee pain needs to be examined to find out the cause of the pain, such as severe meniscus injuries are mainly treated by surgery, osteoarthritis of the knee can be treated by medication and functional exercises, and rheumatoid and rheumatoid arthritis can be treated by medication. Severe meniscus injuries are usually treated with surgery, meniscus suture, meniscus molding, meniscus transplantation and other treatments through arthroscopy, and active rehabilitation training is needed after surgery. Knee osteoarthritis can also cause knee pain. It can be treated with more rest, functional exercise, and medication such as diclofenac sodium extended-release tablets. Rheumatoid and rheumatoid arthritis can cause knee pain and swelling. It is usually treated with medication such as diclofenac sodium extended-release tablets and localized warmth to avoid exposure to cold. Knee pain may also have other causes, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, give targeted treatment or treatment. Drugs need to be used under the guidance of a doctor.