The normal value of neonatal C-reactive protein is less than or equal to 8 μg/ml, when it reaches 12 μg/ml, it belongs to the phenomenon of elevated C-reactive protein, considering that the neonate exists bacterial infections, mycoplasma infections, autoimmune diseases, blood system diseases. 1. Bacterial infection: when the newborn is infected by bacteria, blood tests often show high C-reactive protein and high white blood cells, such as common acute gastroenteritis, which can lead to the phenomenon of increased C-reactive protein in newborns, accompanied by nausea, vomiting and other discomforts. 2. Mycoplasma infection: when mycoplasma infects the body, it can also lead to the phenomenon of increased C-reactive protein, but the white blood cell value is not high, but the proportion of neutrophils is high, such as the common mycoplasma pneumonia. The child is usually accompanied by fever, cough and irritating dry cough. 3. Autoimmune diseases: such as Kawasaki disease, systemic lupus erythematosus, etc., these diseases can also lead to high C-reactive protein, and usually accompanied by vasculitis, but also involved in coronary artery lesions. 4. Blood system diseases: such as common leukemia, lymphoma, etc., when conducting blood tests, C-reactive protein can also be seen to be high. Newborns with elevated C-reactive protein may also be other reasons, should be timely to the hospital to clarify the cause of the disease, under the guidance of the doctor for reasonable treatment.