In recent years, due to the improvement of people’s living standards and changes in lifestyle, the incidence of metabolic diseases represented by fatty liver, hyperlipidemia and hyperuricemia is increasing among young and middle-aged people, and the age has a tendency to decrease year by year. According to their clinical symptoms, most of them have abundant body shape, and analyze their etiology and pathogenesis, most of them are caused by over-eating fatty and sweet food, emotional and mental disorders, and excessive work and rest, resulting in internal injury to the spleen and stomach, which can block qi and turn into fire, and further refine fluid into phlegm, which can lead to blood stasis and form a complex state of qi stagnation, phlegm obstruction and blood stasis. This state is correlated with the development of cardiovascular diseases, diabetes and even tumors, so active physical conditioning is of great social value. It has been shown that the main TCM constitution type for metabolic syndrome is phlegm-damp, and the levels of cholesterol, triglycerides and LDL are significantly higher in patients with phlegm-damp than in patients with other constitution types. In a study of 1163 patients with fatty liver, Liu Junying found that qi deficiency and phlegm dampness were the main body types of fatty liver. In addition, studies on the correlation between certain body types and the development of chronic diseases have become one of the mainstream studies in recent years based on the most commonly disease-causing body types in clinical practice, the most studied of which is phlegm-damp body type. For example, Wang Qi et al. used epidemiological methods to study phlegm-damp body type and related diseases, and found that there was a significant correlation between phlegm-damp body type and the onset of hyperlipidemia, hypertension, coronary heart disease, stroke and diabetes in obese people. The study also found that the substance metabolism, insulin metabolism, and energy metabolism in obese people with phlegm and wetness were significantly higher than those with non-phlegm and wetness in terms of serum total cholesterol (CT), triacylglycerol (TG), and low-density lipoprotein cholesterol (LDL), while the levels of high-density lipoprotein (HDL) and its subfractions were lower than those with non-phlegm and wetness. The objective study of the physical characteristics of phlegmatic humidities by molecular biology and genetic immunology techniques revealed that the antigen spectrum and gene frequencies of human leukocyte antigens, namely HLA-A11, B12, B5, B35 and B40 loci, were significantly higher in phlegmatic humidities than in non-phlegmatic humidities. The peripheral blood gene expression profiles of normal weight individuals, phlegmatic obese individuals, and non-phlegmatic obese individuals were examined by selecting Affymatrix human whole genome microarray U133A with more than 18,000 genes (22,283 probe sets). Fifty-nine genes were differentially expressed in the gene expression profiles of peripheral blood cells of normal and obese individuals, and 115 differentially expressed genes were found in obese individuals with phlegm-dampness versus non-phlegm-dampness. These objectification studies have contributed to the development of TCM somatology and provided a basis for clinical practice.