Stabbing pain in the ankle joint is commonly caused by acute sprain of the ankle joint and gouty synovitis of the ankle joint, as follows: First, acute sprain of the ankle joint: patients with acute sprain of the ankle joint will have symptoms of stabbing pain in the ankle joint, accompanied by joint swelling and restricted activity, which usually occurs when the ankle joint is in plantar flexion position, when the stability of the ankle joint is poor and sprain is easy to occur. Secondly, gouty synovitis of ankle joint: the patient has gouty synovitis of ankle joint, gout crystals are deposited in the ankle joint, stimulating the synovial membrane and causing acute synovial inflammation, the patient can show tingling symptoms of ankle joint, accompanied by limited joint movement. Patients with a clear history of gout and significantly elevated serum uric acid values should be diagnosed and treated early after the occurrence of tingling in the ankle joint in order to completely relieve the symptoms of tingling in the ankle joint, and select the appropriate treatment method after clarifying the cause of the disease to prevent the symptoms from recurring easily.