Kefir is administered anally, with the side effect that it may damage the mucous membranes of the anus or rectum. Keserol is a common topical laxative drug, mainly administered through the anus, the specific mode of operation to remove the cap on the top of the bottle coated with a little grease slowly inserted into the anus, and then the drug will be squeezed into the rectum. The side effect of the drug is that it may damage the mucous membrane of the anus or rectum, but this situation is mainly related to improper operation and has little to do with the drug itself. Keflex is contraindicated in allergic persons and used with caution in allergic persons. Constipated people need to regulate diet, exercise and other lifestyle, to develop good defecation habits, if not improved can be used to assist in the use of drugs to assist in defecation, but under the guidance of a physician to use the correct.