Whether a patient feels chest tightness without fever should not be generalized, but should be diagnosed clearly based on specific symptoms and laboratory tests. If a patient has chest tightness along with clinical manifestations such as malaise and dry cough, it should be noted, but there is no need to be overly alarmed. A small number of patients with novel coronavirus infection may also have symptoms such as nasal congestion, runny nose and diarrhea. Severe cases tend to develop respiratory distress after a week, with rapid progression to acute respiratory distress syndrome, septic shock, and uncorrectable metabolic acidosis in severe cases. If the above symptoms occur, prompt hospital consultation is recommended to detect the presence of novel coronavirus nucleic acid in specimens such as pharyngeal swabs, sputum, lower respiratory secretions, and blood.