When patients develop edema of the eyes and the entire face, it is common for the following diseases: 1. Kidney disease, various causes of glomerulonephritis, can appear symptoms of proteinuria. In this case, the patient can have edema, which can start in the eyelids and the whole face, or in both lower limbs, and in severe cases, the patient can also have generalized edema. 2. Liver disease, hypoproteinemia caused by liver disease, can lead to edema symptoms. In some patients, edema of the eyelids and face can also occur. 3. Heart disease, when heart disease such as heart failure occurs, patients can develop edema. 4. Malnutrition edema, when patients have generalized edema due to malnutrition, edema of the eyelids and face can also occur.