Gastric mesenchymal tumor is now considered to be a submucosal tumor with malignant potential. Gastric mesenchymal tumors lack specific clinical manifestations, most commonly abdominal pain and gastrointestinal bleeding, and the DeMatteo study showed that 47% of cases had metastases by the time clinical manifestations appeared. The diagnosis of gastric mesenchymal tumor is mainly based on barium meal imaging of the upper gastrointestinal tract, gastroscopy, ultrasound endoscopy, and CT, with the higher diagnostic value of ultrasound endoscopy and CT. positive tests for the characteristic immunohistochemical markers CD117 and CD34 are the most diagnostic basis for confirming the diagnosis of gastric mesenchymal tumor, with CD117 being considered the gold standard. Gastric mesenchymal tumors are insensitive to chemotherapy and radiotherapy, and the only effective treatment is resection of the tumor. Some studies have reported that imatinib (Gleevec) is effective for malignant mesenchymal tissue-derived tumors, but it has not been widely used in the clinic due to its high price and uncertainty of efficacy. The fact that gastric mesenchymal tumors are less likely to have lymph node metastases and do not require radical surgery for lymph node dissection, and that regular gastrectomy is not necessary, provides more room for minimally invasive laparoscopic treatment of gastric mesenchymal tumors to operate. Gastroscopic resection of gastric mesenchymal tumors carries the risk of inadequate resection coverage, as well as the risk of concomitant bleeding and perforation. Laparoscopic resection of gastric mesenchymal tumor can achieve the required resection extent under direct vision surgery without destroying the tumor and reducing local recurrence. In recent years, there have been more and more reports on minimally invasive surgical treatment of gastric mesenchymal tumors at home and abroad, and the results have confirmed that compared with traditional open surgery, laparoscopic surgery does not differ in terms of operating time and intraoperative bleeding, but has significant advantages in terms of postoperative recovery and postoperative hospitalization time.