The soreness of the buttocks and thighs may be caused by the following diseases: 1. Special occupations that often squat, physical labor, poor working life and living conditions can lead to the emergence of pear-shaped muscle syndrome, which is caused by inflammation of the pear-shaped muscle caused by external or exertional injury stimulation, swelling of the pear-shaped muscle compressing the sciatic nerve, thus causing soreness of the buttocks and legs. The patient will also have the symptom of leg numbness, and serious patients can have claudication and muscle atrophy. 2, long-term lumbar fixed posture, people suffering from lumbar disc herniation will also have hip and leg pain symptoms, and most patients also have lumbago symptoms. The symptoms can be aggravated after bending, straining and sitting, and can be relieved after rest and sleep. 3. People who do not exercise frequently can also suffer from hip and leg pain due to lactic acid accumulation, subtle muscle damage and inflammatory stimulation after strenuous activities.