At present, there is still a lack of more effective treatment for melasma, which can be lightened or eliminated by medication and physical therapy. Hydroquinone cream is the first-line drug for melasma treatment. The higher the concentration of this product, the better the treatment effect, but the greater the stimulation to the skin. Adverse reactions such as burning sensation and localized allergy can be seen with the use of hydroquinone cream. It is prohibited for pregnant women, children under 12 years old and those who are allergic to this product. Physical therapy, including laser therapy and intense pulse therapy, can be used to treat stubborn melasma. There is a risk of scar formation or even keloid after physical therapy. If melasma appears on the face, it is recommended to go to the hospital in time and have standardized treatment as soon as possible under the guidance of professional doctors. The medication should be used according to the doctor’s prescription, do not use the medication on your own.