The probability of hepatitis E positive igm not turning negative is very small, it is relatively easy to recover after active treatment, and most patients have a good prognosis. Hepatitis E antibodies are categorized into IgM antibodies and IgG antibodies. After infection with the virus, IgM antibodies appear more quickly and fade faster, and IgM antibody positivity is often in the period of infection, whereas IgG antibodies may be persistent, and IgG antibody positivity may be a result of a previous infection. Hepatitis E usually causes short-term, acute liver injury and does not usually lead to long-term recurrent damage to liver cells. In summary, the probability of hepatitis E positive igm not turning negative is very small, usually after the condition of hepatitis E improves the igm antibody will turn negative, it is recommended that the infection of hepatitis E should be actively treated, to prevent the condition from worsening leading to serious liver injury or even death.