Belly and testicular skin prickling itch is not necessarily uremia, but can also be seen in eczema, dermatitis and so on. In addition to itchy skin, uremia is often accompanied by other systemic symptoms and elevated biochemical indicators. Uremia is the common outcome of various chronic kidney diseases that continue to progress to the late stage. It is a clinical syndrome characterized by metabolite retention, imbalance of water, electrolyte and acid-base balance and systemic symptoms, which can be manifested as itchy skin, nausea and vomiting, loss of appetite, edema, chest tightness, dyspnea and so on, and renal function suggests elevated blood creatinine, urea nitrogen and so on. Eczema is an inflammation of the superficial dermis and epidermis caused by a variety of internal and external factors, clinically acute lesions are dominated by pemphigus with a tendency to ooze, and chronic lesions are dominated by mossy lesions, which are prone to recurrent episodes. The main symptom is intense itching, the skin can appear pimples, small blisters, etc., preferably in the head, face, limbs, scrotum and other parts of the head and face, usually without the manifestation of abnormal renal function. Dermatitis is an inflammatory disease of the skin caused by a variety of infectious or non-infectious factors, manifested as skin patches, blisters, plaques, vesicles, mossy changes, etc., and there is no manifestation of abnormal renal function. Belly and testicular skin prickling patients, it is recommended to go to the regular hospital, the doctor line related examinations to clarify the diagnosis and give treatment.