The main symptoms of limb-girdle muscular dystrophy are as follows: 1. The primary symptom of the patient is mainly muscle atrophy of the trunk muscles, such as the pelvic girdle muscles, and the patient can develop lumbar lordosis and duck step when walking. Proximal weakness of the lower extremities and difficulty in lifting the legs when going upstairs. It is also possible to develop atrophy of the scapular girdle muscles, making it difficult to lift the head, arms or comb the hair.2. Some patients can also develop myocardial damage, manifesting as increased cardiac enzymes and limb-girdle muscular dystrophy. It is a hereditary disease, mainly autosomal recessive inheritance, the general age of onset is adolescents, but some show adult onset, most patients can appear myogenic damage of electromyography. Patients can be incapacitated about 20 years after the onset of the disease, and the facial muscles are usually not involved in limb-girdle muscular dystrophy.