Ocular calculus is actually a solid substance mixed with mucus secretions and shedding cells of the conjunctiva. This kind of stone collects under the conjunctiva and can be left untreated if it does not protrude from the surface. If the stones protrude from the surface, because of their hard texture, they may cause irritation to the human eye causing foreign body sensation, like stones we have to remove them. The most important thing for stone prevention is to treat the primary disease, such as chronic conjunctivitis and trachoma, we should treat the chronic conjunctivitis and trachoma properly so that the stones cannot recur, like trachoma, the standardized treatment is to order rifampin, sulfacetamide sodium ophthalmic solution, pay attention to hygiene, wash hands regularly, the course of treatment may reach about three months to six months. In addition, chronic conjunctivitis treatment is also standardized eye drops, may also last longer, like chronic conjunctivitis and trachoma are to adhere to treatment, inflammation subsided after the stone will not occur again.