Patients with glaucoma are usually treated with medication, laser or surgery to control IOP. Topical medications include topical and systemic medications. Topical medications are mainly eye drops, which can be used in one or several combinations, such as the beta-blocker timolol eye drops, the cholinomimetic drug maurobrine eye drops, the carbonic anhydrase inhibitor brinzolamide eye drops, the alpha-adrenergic agonist alphagen eye drops, and the prostaglandin derivative travoprost eye drops. Systemic medications are mainly used to reduce intraocular pressure by using hypertonic dehydrating agents such as mannitol to dehydrate the eye, and some patients can be treated with laser trabeculoplasty. For patients with severe glaucoma who do not do well with medication, surgical pressure-lowering treatment is usually considered. The most common surgical procedure is filtration surgery, which includes trabeculectomy, scleral occlusion, and drainage staple and drainage valve implantation.