Estrogen levels will not decrease after taking Eusemide. Although Eusemide is a short-acting oral contraceptive, it is a compound preparation of estrogen and progestin, and its active ingredients are ethinyl estradiol and drospirenone. Taking Eusemide can adjust the menstrual cycle and can supplement estrogen, so taking Eusemide will generally not cause estrogen levels to decrease. Some women may experience a decrease in menstrual flow after taking Eusebio because the process of taking Eusebio may cause thinning of the endometrium, but after stopping the drug, if the endocrine level is normal and does not affect menstruation, the menstrual flow may return to normal, so there is no need to worry about a decrease in estrogen level after taking Eusebio.