Herpes zoster is caused by the varicella-zoster virus and is characterized by small blisters distributed along one side, often accompanied by significant neuralgia. When a person is infected with the virus, varicella can occur or be latently infected, and then the virus is latent in the ganglion; when the body is stimulated in some way (such as trauma, fatigue, malignant tumor or post-illness weakness, etc.) resulting in a decrease in body resistance, the latent virus is activated, causing the onset of the disease, producing blisters, and at the same time the affected nerves become inflamed and necrotic, producing neuralgia. The disease is usually not recurring because of the long-lasting immunity after recovery. The prevalent sites are the intercostal nerve, cervical nerve, trigeminal nerve and lumbosacral nerve innervation areas in that order. The lesions are arranged in a band along one of the peripheral nerves, mostly on one side of the body, and usually do not exceed the midline. Neuralgia is one of the characteristics of the disease and may occur before the onset of the disease or with the lesions, and is often more intense in older patients. The duration of the disease is usually 2 to 3 weeks, and 3 to 4 weeks in the elderly. In addition to typical herpes zoster manifestations, there are also some special manifestations: 1. ocular herpes zoster: mostly seen in the elderly, the pain is severe and can involve the cornea to form ulcerative keratitis. 2. Ear herpes zoster: It is caused by viral invasion of the facial and auditory nerves and manifests as herpes of the external auditory canal or tympanic membrane. Facial palsy, ear pain and herpes triad in the external auditory canal may occur. 3. Postherpetic neuralgia: Herpes zoster is often accompanied by neuralgia, but it mostly disappears after the lesions have completely faded or within 1 month, and in a few patients the neuralgia can last for more than 1 month, which is called postherpetic neuralgia. 4, other atypical herpes zoster: caused by differences in the resistance of the patient’s body, can be manifested as strophic (no lesions only neuralgia), incomplete (only erythema, papules without blisters that recede), maculopapular, hemorrhagic, gangrenous and generalized; the virus can occasionally be disseminated through the blood to produce a widespread varicella-like rash and invade the lungs and brain and other organs, called disseminated herpes zoster. Treatment principles: the earlier the onset of treatment, the better, delayed treatment increases the occurrence of neuralgia sequelae, treatment principles for antiviral, analgesic, anti-inflammatory, prevention and control of secondary infection and sequelae of neuralgia. 1, systemic treatment: antiviral drugs, pain relief, glucocorticoids. 2. Topical medication: dryness and anti-inflammation. If combined with eye damage must ask the ophthalmologist to deal with. 3, physical therapy: semiconductor laser, etc., can relieve pain, promote blister drying and crusting.