9-year-old girl with high estrogen, if the general mildly elevated, no other symptoms, can be adjusted by adjusting the diet, improve the lifestyle management; if the elevation of more, need to consider precocious puberty, need to target the cause of the treatment. 1. General mild elevation without other symptoms: can be adjusted diet, eat more vitamin-rich food, avoid high fat, high sugar and high salt diet. It is also necessary to improve the lifestyle, to ensure regular work and rest habits, to avoid sleeping late, staying up late, etc., strict control of body weight, and maintain a good mood. 2. Precocious puberty: Children with precocious puberty may have high estrogen, pre-pubertal development of secondary sexual characteristics, accelerated bone maturation and other symptoms. Treatment should be based on the cause of the disease. For central precocious puberty, drugs such as treprostinil and leuprolide extended-release agent can be taken according to the doctor’s instruction. For tumors, surgery, chemotherapy and radiotherapy are required. Those caused by hypothyroidism take thyroid preparations. Therefore, medication should be taken under the guidance of a medical professional.