The cause of menopausal leg pain may be caused by osteoporosis, muscle spasm, neuritis, rheumatism, etc. You can take non-steroidal anti-inflammatory drugs, muscle relaxing drugs, vitamin drugs, neurotrophic drugs and so on. 1. Non-steroidal anti-inflammatory drugs: commonly used drugs include etoricoxib, ibuprofen extended-release tablets, meloxicam, etc., which can play a role in relieving pain. 2. Muscle relaxing drugs: such as ethisterone hydrochloride drugs, can relieve the symptoms of muscle spasm in the legs and other symptoms, reduce pain symptoms. 3. Vitamins: Due to poor calcium absorption during menopause, cartilage damage can easily lead to leg pain, etc. Taking vitamin D and calcium tablets can radically improve the phenomenon of osteoporosis. 4. Neurotrophic drugs: For example, the use of methylcobalamin and other drugs, play a role in the nutrition of the nerves, restore nerve function, thereby improving pain and discomfort. All of the above medications should be used under the guidance of a doctor, avoiding self-medication, so as to avoid adverse consequences.