Alcohol intoxication on the patient first from mild excitement and then suppression, early patients tend to appear active thinking, talking more, accompanied by facial flushing and rapid heartbeat, with the further increase in the amount of alcohol, the patient will gradually appear a variety of muscle movement uncoordinated, unstable gait, further aggravated or even drowsiness, coma. In this state it is easy to have respiratory and circulatory failure leading to death, or due to vomiting the patient is unconscious and can easily cause asphyxiation, causing respiratory obstruction, or death due to lack of oxygen and apnea. So alcohol poisoning leads to death, most of them are not discovered, all quietly, and by the time they are brought to the hospital emergency department, the patient has no vital signs. So there are no very special clinical signs of death from alcohol poisoning, it is recommended that drinking must be moderate, and if you drink too much alcohol you must seek medical attention in time.