Both montelukast and norfloxacin can treat acute gastroenteritis, but the biggest difference between the two lies in the pharmacology. The main component of montelukast is montmorillonite, which can have a fixed and inhibitory effect on bacteria in the gastrointestinal tract after taking montelukast, but montelukast itself does not have the effect of killing bacteria. In addition, montmorillonite can form a barrier with the mucous membrane of the gastrointestinal tract, which can reduce the invasion of bacteria and other harmful substances in the gastrointestinal tract. And norfloxacin is a quinolone antibiotic, which is a synthetic antibiotic, mainly through the inhibition of cell wall production to achieve the role of killing bacteria, which is an antibiotic, so the main components and the main pharmacological effect of montelukast and norfloxacin is the biggest difference.