There are many causes of mouth bitterness and nausea, which need to be analyzed according to two aspects, Chinese medicine perspective and western medicine perspective. Chinese medicine is generally considered to be caused by the exuberant stomach fire, while western medicine is mainly caused by liver and gallbladder inflammation, gastroesophageal reflux disease, peptic ulcer, etc. Reasonable treatment needs to be given according to the specific causes to improve the symptoms of mouth bitterness and nausea. First, from the perspective of traditional Chinese medicine, bitterness in the mouth and nausea need to be considered as a possible cause of stomach fire. It is recommended to ensure a good mood, take stomach clearing Huanglian tablets, spleen pills and other treatment, diet can eat bitter melon, bitter chrysanthemum and other fire-defeating food to regulate. Second, the western medical perspective 1, liver and biliary inflammation: such patients are prone to bile reflux, resulting in patients with nausea, bitter mouth symptoms, may be accompanied by abdominal distension, indigestion, etc., can be under the guidance of doctors oral omeprazole, domperidone, anti-inflammatory bile tablets, magnesium aluminum carbonate treatment. At the same time, we should pay attention to dietary regimen and develop good eating habits and living rules. In the diet should eat more easily digestible food, such as porridge, noodles, millet porridge, rice porridge, corn porridge, etc., avoid eating some cold, greasy, spicy, irritating food; 2, gastroesophageal reflux disease: gastroesophageal reflux patients who have nausea, bitter mouth symptoms, may be bile reflux into the stomach, and then through the gastric reflux to the esophagus caused by bile stimulation, and the phenomenon of bitterness in the mouth, nausea. At this time, patients should promptly consult a doctor, follow medical advice to take H2 receptor blockers, proton pump inhibitors and prokinetic drugs, magnesium aluminum carbonate, if necessary, endoscopic or surgical treatment; 3, peptic ulcer: such as gastric, duodenal ulcer, etc., due to gastrointestinal power deficiency, may lead to delayed gastrointestinal emptying, food in the gastrointestinal stay longer, triggering symptoms of bitter mouth, nausea, some patients may be accompanied by abdominal distension, acid reflux Some patients may have symptoms such as bloating, acid reflux, heartburn, etc. Patients should go to the hospital for relevant examinations, such as gastroscopy, colonoscopy, Helicobacter pylori testing, etc., to clarify the cause, give medication, avoid excessive stress and exertion, and strengthen dietary regimen.